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Celery Been Shown to Lower Blood Pressure & Fight Against Cancer
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Celery
Seed Helps
Prevent Formation of Cancerous Tumors in Mice
Source:
http://www.healthandage.com/html/res/com/ConsHerbs/CelerySeedch.html |
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| Botanical
Name: |
Apium
graveolens |
| Preliminary
animal studies have also found that celery seed helps
prevent the formation of cancerous tumors in mice. |
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| Overview |
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Celery
seed is one of the lesser-known herbs in Western herbal
medicine. However, it has been used for thousands of years in
other parts of the world for a variety of reasons. During
ancient times, Ayurvedic physicians (vaidyas) used celery seed
to treat people with colds, flu, water retention, poor
digestion, various types of arthritis, and certain ailments of
the liver and spleen.
Today,
celery seed is used primarily as a diuretic to promote the
excretion of urine. The diuretic action combined with the
presence of anti-bacterial compounds in celery seed also make it
useful in treating urinary tract infections. Laboratory studies
have found that compounds in celery seed and its essential oil
may also help reduce muscle spasms, calm the nerves, and reduce
inflammation. In fact, some experts claim that celery seed
alleviates the pain associated with certain inflammatory health
conditions such as arthritis and gout.
In
addition, a few animal studies suggest that celery seed extracts
may have activity to help lower blood pressure and cholesterol
as well as protect the liver from damaging agents such as
acetominophen (also called paracetamol; an over the counter
medication for pain and headache that can cause liver damage if
taken in large quantities.)
None
of these claims, however, have not been studied in people to
date or backed by rigorous scientific studies. So, further
research is needed to determine the safety and effectiveness of
celery seed for the conditions described.
Preliminary
animal studies have also found that celery seed helps prevent
the formation of cancerous tumors in mice. In a study that
included large numbers of people with and without colorectal
cancer, researchers found that people who consumed a diet rich
in lutein (from celery, spinach, broccoli, lettuce, tomatoes,
oranges, carrots, and greens) were significantly less likely to
develop colorectal cancer. It is not clear, however, whether
celery alone played an important role in the prevention of this
disease and how the information about these whole foods relates
to the extracts and isolates of celery seed.
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| Plant
Description |
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The
celery plant is slender and stands about two to three feet tall.
It has three to five segmented leaves, and flowers with small
white petals. Celery seeds, which are found in the flowers, are
very small, tan to dark brown, and have a strong, pleasant
smell.
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| What's
It Made Of? |
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Celery
seeds contain several substances including volatile oils,
flavonoids, coumarins, and linoleic acid.
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| Available
Forms |
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- Fresh
or dried seeds
- Tablets
- Capsules
filled with celery seed oil
- Celery
seed extract, in which the active ingredients of celery seed
have been extracted by alcohol or glycerin
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| How
to Take It |
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Pediatric
There
are no known scientific reports on the pediatric use of celery
seed. Therefore, it is not currently recommended for medicinal
purposes in children.
Adult
Celery
seed oil capsules or tablets: One to two capsules or tablets
three times a day, as directed by your health care provider.
Celery
seed extract: 1/4 to 1/2 tsp three times a day, or as directed
by your health care provider. (Always take with plenty of juice
or with water at mealtime, unless instructed otherwise.)
Whole
celery seeds: Prepare a tea by pouring boiling water over one
teaspoon (1 to 3 g) of freshly crushed seeds. Let it steep for
10 to 20 minutes before drinking. Drink three times a day.
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| Precautions |
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The
use of herbs is a time-honored approach to strengthening the
body and treating disease. Herbs, however, contain active
substances that can trigger side effects and that can interact
with other herbs, supplements, or medications. For these
reasons, herbs should be taken with care, under the supervision
of a practitioner knowledgeable in the field of botanical
medicine.
Pregnant
women should not use celery seed because it may uterine bleeding
and cause muscle contractions in the uterus.
People
with active kidney inflammation should also avoid this herb.
Although
uncommon, allergic reactions (even anaphylaxis) to celery seed
may develop in people who handle or ingest celery. In fact, some
individuals who are allergic to birch pollen may also be
allergic to celery seed.
Active
compounds in celery stems and seeds can cause the skin to become
highly sensitive to UV rays (called photodermatitis). For this
reason, people taking celery seed should use sunscreen or
sunblock lotions to protect their skin from the sun.
Celery
seeds should not be taken from a garden packet. Most seeds sold
for these purposes have been treated with chemicals and should
not be taken internally.
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| Possible
Interactions |
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There
are no known scientific reports of interactions between celery
seed and conventional medications. However, given that celery
seed is an herb with diuretic effects, people taking
prescription diuretics (such as furosemide or
hydrochlorothiazide) should not take this herb without first
consulting a healthcare provider.
Similarly,
celery contains properties that may thin the blood, thus making
it somewhat of a concern to take with blood thinning medications
such as warfarin or aspirin. If you take warfarin in particular
you should not use celery seed without first consulting your
healthcare provider.
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| Supporting
Research |
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Atta
AH, Alkofahi A. Anti-nociceptive and anti-inflammatory effects
of some Jordanian medicinal plant extracts. J Ethnopharmacol.
1998;60:117–124.
Banerjee
S, Sharma R, Kale RK, Rao AR. Influence of certain essential
oils on carcinogen-metabolizing enzymes and acid-soluble
sulfhydryls in mouse liver. Nutr Cancer. 1994;21:263–269.
Abstract.
Blumenthal
M, ed. The Complete German Commission E Monographs: Therapeutic
Guide to Herbal Medicines. Boston, Mass: Integrative Medicine
Communications; 1998:35-36; 214-215; 245-249.
Boffa
MJ, Gilmour E, Ead RD. Case report. Celery soup causing severe
phototoxicity during PUVA therapy [letter]. Br J Dermatol.
1996;135(2):334.
Brinker
F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy,
OR: Eclectic Medical Publications; 1998:52-53.
Duke
JA. Handbook of Phytochemical Constituents of GRAS Herbs and
Other Economic Plants. Boca Raton, Fla: CRC Press; 1992.
Foster
S, Tyler VE. Tyler's Honest Herbal. 4th ed. New York: The
Haworth Herbal Press; 1999:101-103.
Heck
AM, DeWitt BA, Lukes AL. Potential interactions between
alternative therapies and warfarin. Am J Health Syst Pharm.
2000;57(13):1221-1227.
Ko
FN, Huang TF, Teng CM. Vasodilatory action mechanisms of
apigenin isolated from Apium graveolens in rat thoracic aorta.
Biochim Biophys Acta. November 14; 1991;1115:69–74.
Leung
AY, Foster S. Encyclopedia of Common Natural Ingredients Used in
Food, Drugs and Cosmetics. 2nd ed. New York, NY: Wiley and Sons;
1996.
Miller
L. Herbal medicinals: selected clinical considerations focusing
on known or potential drug-herb interactions. Arch Intern Med.
1988;158(20):2200–2211.
Newall
CA, Anderson LA, Phillipson JD. Herbal Medicine: A Guide for
Health-care Professionals. London: The Pharmaceutical Press;
1996.
Ottariano
SG. Medicinal Herbal Therapy. Portsmouth, NH: Nicolin Fields
Publishing; 1999; 82.
Singh
A, Handa SS. Hepatoprotective activity of Apium graveolens and
Hygrophila auriculata against paracetamol and thioacetamide
intoxication in rats. J Ethnopharmacol. 1995;49:119–126.
Slattery
ML, Benson J, Curtin K, Ma K-N, Schaeffer D, Potter JD.
Carotenoids and colon cancer. Am J Clin Nutr. 2000;71:575-582.
Teng
CM, Lee LG, Ko SN, et al. Inhibition of platelet aggregation by
apigenin from Apium graveolens. Asia Pac J Pharmacol. 1985;3:85.
Tsi
D, Das NP, Tan BK. Effects of aqueous celery (Apium graveolens)
extract on lipid parameters of rats fed a high fat diet. Planta
Med. 1995;61:18–21.
Zheng
GQ, Kenney PM, Zhang J, Lam LK. Chemoprevention of
benzo[a]pyrene-induced forestomach cancer in mice by natural
phthalides from celery seed oil. Nutr Cancer. 1993;19:77–86.
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| Review
Date: April 2002 |
Reviewed
By: Participants in the review process include: Steven Dentali,
PhD (April 1999), Senior Director of Botanical Science, Rexall
Sundown, Boca Raton, FL; Jacqueline A. Hart, MD, Department of
Internal Medicine, Newton-Wellesley Hospital, Harvard University
and Senior Medical Editor Integrative Medicine, Boston, MA; Gary
Kracoff, RPh (Pediatric Dosing section February 2001), Johnson
Drugs, Natick, MA; Steven Ottariono, RPh, Veteran's
Administrative Hospital, Londonderry, NH; R. Lynn Shumake, PD
(April 1999), Director, Alternative Medicine Apothecary, Blue
Mountain Apothecary & Healing Arts, University of Maryland
Medical Center, Glenwood, MD; Tom Wolfe, P.AHG (April 1999),
Smile Herb Shop, College Park, MD. All interaction sections have
also been reviewed by a team of experts including Joseph Lamb,
MD (July 2000), The Integrative Medicine Works, Alexandria, VA; Enrico
Liva, ND, RPh (August 2000), Vital Nutrients, Middletown, CT;
Brian T Sanderoff, PD, BS in Pharmacy (March 2000), Clinical
Assistant Professor, University of Maryland School of Pharmacy;
President, Your Prescription for Health, Owings Mills, MD; Ira
Zunin, MD, MPH, MBA (July 2000), President and Chairman, Hawaii
State Consortium for Integrative Medicine, Honolulu, HI.
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The
publisher does not accept any responsibility for the accuracy of
the information or the consequences arising from the
application, use, or misuse of any of the information contained
herein, including any injury and/or damage to any person or
property as a matter of product liability, negligence, or
otherwise. No warranty, expressed or implied, is made in regard
to the contents of this material. No claims or endorsements are
made for any drugs or compounds currently marketed or in
investigative use. This material is not intended as a guide to
self-medication. The reader is advised to discuss the
information provided here with a doctor, pharmacist, nurse, or
other authorized healthcare practitioner and to check product
information (including package inserts) regarding dosage,
precautions, warnings, interactions, and contraindications
before administering any drug, herb, or supplement discussed
herein.
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