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NEW Cancer Drug Attacks
Cancerous Cells Without Damaging Healthy Tissue
Source:
manchesteronline.co.uk/news/
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Go-ahead given for New cancer drug
Rebecca Camber
A NEW cancer drug
developed and tested at the Christie Hospital has been given the green light.
Scientists at the hospital's Paterson Research Institute are celebrating after
the drug, which attacks cancerous cells without damaging healthy tissue, was
given a license for commercial development.
Full trials will be completed next year, meaning the drug could be available to
patients within five years. If the drug fulfils its early potential, it could
save millions of lives.
Researchers at the research institute have spent years perfecting the drug,
named RH1, which was first developed by Dr Malcolm Ranson.
Last September, the
Christie Hospital held the first trials of the drug which, unlike chemo and
radiotherapy, can distinguish between normal tissue and cancerous cells.
The drug is
activated by an enzyme mass produced in cancerous tumours, which it uses to seek
out cancer cells and destroy them.
The treatment will offer new hope for patients who have already failed to
respond to conventional cancer treatments. In the past year, 12 patients have
taken part in the trials sponsored by Cancer Research UK.
Safety
Researchers had
planned to recruit another 28 patients for the trial over the next year, but the
results have already proved so successful that a US biopharmaceutical company
has now obtained permission to develop the drug further.
It has acquired a worldwide license from the University of Colorado Health
Sciences Center, the University of Salford and Cancer Research Technology to
develop and commercialize the drug.
Dr Malcolm Ranson, who runs the clinical trial unit at the Christie Hospital,
said: "The successful development of this drug is a true credit to the
cancer research teams here in Manchester. It's a fantastic example of how local
teams have taken research from the laboratory all the way to the patient. It's
wonderful that local patients are the first to benefit from this development in
cancer treatment.
"We've enrolled nearly a third of the desired number of patients for the
study and are encouraged by results seen to date from both a safety and efficacy
standpoint.
"Clinical trials are the vital step in developing better treatments for
cancer patients. They improve the quality of care, which at the end of the day
is what all cancer research work is about."
Aloha From Hawaii!
Dec 2004 Prostate
Cancer News
NEW Cancer Drug Attacks Cancerous
Cells Without Damaging Healthy Tissue
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Drug Attacks Cancerous Cells Without Damaging Healthy Tissue

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